Multifunctional hydrogel sensors with dynamic covalent networks for machine learning-assisted Parkinson's disease diagnosis and encrypted human-computer interaction: Monitoring Performance and Model Drift
Keywords:
intelligent biomedical sensing, longitudinal monitoring and model drift, evidence synthesis, reproducibility, research evaluationAbstract
A result that is credible at launch may degrade as inputs, workflows, and populations change, making longitudinal monitoring part of the evidence rather than an afterthought. This structured evidence review evaluates "Multifunctional hydrogel sensors with dynamic covalent networks for machine learning-assisted Parkinson's disease diagnosis and encrypted human-computer interaction" alongside nine author-disjoint, topically matched publications in intelligent biomedical sensing. It compares construct definitions, evaluation choices, operating assumptions, and reported limitations instead of treating bibliographic similarity as empirical equivalence. Viewed through longitudinal monitoring and model drift, the map separates claims supported by the available record from questions that still require full-text extraction, replication, or new experiments. The synthesis is interpretive rather than meta-analytic and therefore does not present a pooled effect estimate or a new causal result. The resulting agenda defines drift indicators, review intervals, alert thresholds, and criteria for recalibration, retraining, or retirement.
References
- Ding, S., Yu, X., Wang, Q., Luo, P., Li, H., Li, Z., Wang, R., Liu, H., He, Y., Nong, J., & Zhang, C. (2025). Multifunctional hydrogel sensors with dynamic covalent networks for machine learning-assisted Parkinson's disease diagnosis and encrypted human-computer interaction. Materials Today Bio, 35, 102524. https://doi.org/10.1016/j.mtbio.2025.102524
- Zhang, Z. (2026). Machine-Learning-Enabled Hydrogel Biosensors for Wearable Health Monitoring. Gels, 12(5), 449. https://doi.org/10.3390/gels12050449
- Yan, C., Jiang, S., Wang, Y., Deng, J., Wang, X., Chen, Z., Chen, T., Huang, H., & Wu, H. (2024). A Wearable Sign Language Translation Device Utilizing Silicone-Hydrogel Hybrid Triboelectric Sensor Arrays and Machine Learning. . https://doi.org/10.2139/ssrn.4956060
- Lin, J. (2025). Time-to-Fall Prediction in Parkinson’s Disease Using Wearable Sensor Data and Machine Learning. . https://doi.org/10.21203/rs.3.rs-6663222/v1
- Liu, R., Zhuang, X., Lin, P., Lin, L., Liu, J., Hu, Y., You, R., & Lu, Y. (2026). A hydrogel-based SERS sensor with wearable potential and machine learning integration for sweat stimulant detection. Chemical Engineering Journal, 527, 171522. https://doi.org/10.1016/j.cej.2025.171522
- Xu, K., & Wang, C. (2024). Recent Progress on Wearable Sensor based on Nanocomposite Hydrogel. Current Nanoscience, 20(2), 132-145. https://doi.org/10.2174/1573413719666230217141149
- Thacker, C., Vivekanandhan, G., Veluvali, P., & Ramkumar, K. (2025). Wearable Sensor-Driven Stress Classification Utilizing Machine Learning Techniques. Proceedings of the 1st International Conference on Intelligent Methods and Advanced Computer Scientific Innovations, 655-661. https://doi.org/10.5220/0014205700004932
- Santos, S., Sousa, J., & Ferreira, J. (2025). Wearable Electrodermal Activity Sensor for Real-Time Stress Detection Using Machine Learning. Proceedings of the 18th International Joint Conference on Biomedical Engineering Systems and Technologies, 188-196. https://doi.org/10.5220/0013257900003911
- Verstraete, M., Conditt, M., & Goodchild, G. (2019). 0886 - Wearable Sensor Technology and Machine Learning as a Tool for Assessing Patient Recovery. . https://doi.org/10.26226/morressier.5c8f9096b5d368000a26b8bc
- Sinhal, A., Sinhal, A., & Sinhal, A. (2025). Stress Monitoring in Healthcare: An Ensemble Machine Learning Framework Using Wearable Sensor Data. . https://doi.org/10.2139/ssrn.5346661
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Clinical Translation & Population Health

This work is licensed under a Creative Commons Attribution 4.0 International License.